Family GP001269


Family ID GP001269  add to my list RDF
Family name Cobalamin-independent methionine synthase family   suggest a name
Synonym(s) 5-methyltetrahydropteroyltriglutamate , homocysteine s-methyltransferase
Cross-reference(s) PMID:
Crystal structures of cobalamin-independent methionine synthase complexed with zinc, homocysteine, and methyltetrahydrofolate.
15326182
Family Ontology
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molecular_function
5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
GO:0003871 (81%) - 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
Curation status ?
Found in No specificity
Phylogenetic analyzes Did not pass filtration




Clustering level Family ID (number of sequences)
1
Cobalamin-independent methionine synthase family
GP001269 (231)
2 GP016311 (231)
3 GP040939 (231)
4 GP070347 (231)
Table 1: This table displays which relationship has the selected family with other families in GreenPhyl clustering ?.




Legend:
  • Families (clustering)
    • Sequences are clustered and classified at 4 levels (from less to more stringent).
    • The number between parenthesis indicates the number of sequences in the cluster.
    • Selected family is highlighted like this.
    • Annotated gene families are underlined and gene family name pops up when you move your mouse cursor over.
    • Gene families are coloured in this color when the phylogenetic analyses are available.


Sequence total: 231
Species Count (w/o splice) Count (w/ splice)
1 1
1 1
5 10
1 1
30 30
2 2
4 4
4 4
7 7
7 7
2 4
3 3
4 4
2 2
3 13
2 5
1 1
2 2
2 2
4 4
3 7
2 2
6 6
6 23
2 2
5 27
2 2
6 6
3 3
6 6
8 8
4 6
3 3
4 4
11 16
3 3


Information to display




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Close InterPro family
IPR Annotation Type % Occurence Specificity
Cobalamin-independent methionine synthase
IPR006276
Cobalamin-independent methionine synthase Family 56 (130) Yes
Methionine synthase, catalytic subunit-predicted, cobalamin-independent
IPR016456
Methionine synthase, catalytic subunit-predicted, cobalamin-independent Family 1 (1) Yes

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
Methionine synthase, vitamin-B12 independent
IPR002629
Methionine synthase, vitamin-B12 independent Domain 81 (187) No

Close Domain architecture
Clustering
 



Close Representative InterPro domains - Consensus schema
IPR006276 IPR002629
Cobalamin (vitamin B12)-independent methionine synthase MetE, N-terminal
IPR013215



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Species
Information to display
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Alignment not available.
[Masking step 1 details] [Masking step 2 details] [Filtration details] [Global HMM file]

Phylogeny tree not available.


Alignment and filtration statistics:

Overall family sequences Sequences used for alignment (w/o splice) Sequences kept after filtration [min; median; max] ~average sequence length Alignment length Masked alignment length
231 161 (70%) 116 (50%) [52; 764; 832] ~610 1304 764