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Family GP001544


Family ID GP001544  add to my list RDF
Family name Spo11/DNA topoisomerase VI, subunit A family   suggest a name
Cross-reference(s) PMID:
AtSPO11-1 is necessary for efficient meiotic recombination in plants.
11157765 PMID:
The catalytically active tyrosine residues of both SPO11-1 and SPO11-2 are required for meiotic double-strand break induction in Arabidopsis.
17965269 PMID:
A crucial role for the putative Arabidopsis topoisomerase VI in plant growth and development.
12119417
Comment
Family Ontology
Close Hide
molecular_function
protein binding
GO:0005515 (1%) - protein binding
Curation status ?
Found in No specificity
Phylogenetic analyzes Did not pass filtration




Clustering level Family ID (number of sequences)
1
Spo11/DNA topoisomerase VI, subunit A family
GP001544 (176)
2
Spo11/DNA topoisomerase VI, subunit A family
GP016719 (174)
3 GP041957 (129) ,
(plant-specificity: 9%)
GP047812 (43)
4 GP074789 (77) , GP075012 (52) ,
(plant-specificity: 9%)
GP077135 (43)
Table 1: This table displays which relationship has the selected family with other families in GreenPhyl clustering ?.




Legend:
  • Families (clustering)
    • Sequences are clustered and classified at 4 levels (from less to more stringent).
    • The number between parenthesis indicates the number of sequences in the cluster.
    • Selected family is highlighted like this.
    • Annotated gene families are underlined and gene family name pops up when you move your mouse cursor over.
    • Gene families are coloured in this color when the phylogenetic analyses are available.


Sequence total: 176
Species Count (w/o splice) Count (w/ splice)
4 4
2 2
9 9
4 6
6 6
9 9
3 3
3 3
3 3
2 2
2 2
5 5
3 3
2 2
3 3
3 9
3 3
4 4
4 4
4 4
3 3
3 3
4 4
6 6
3 4
3 3
3 4
4 4
3 3
5 5
13 13
13 13
8 8
3 3
3 3
4 8
3 3


Information to display




(click on chart bars above to get species proteins)


Close InterPro family
IPR Annotation Type % Occurence Specificity
Spo11/DNA topoisomerase VI, subunit A
IPR002815
Spo11/DNA topoisomerase VI, subunit A Family 88 (154) No
DNA topoisomerase VI, subunit A
IPR004085
DNA topoisomerase VI, subunit A Family 26 (46) Yes
Meiotic recombination, Spo11
IPR013048
Meiotic recombination, Spo11 Family 18 (31) Yes

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
Winged helix-turn-helix DNA-binding domain
IPR011991
Winged helix-turn-helix DNA-binding domain Domain 68 (119) No

Close Domain architecture
Clustering
 



Close Representative InterPro domains - Consensus schema
IPR011991 IPR002815
Spo11/DNA topoisomerase VI, subunit A, N-terminal
IPR013049



Build your own display:   ?

Species
Information to display
?


(click on the button above to get your protein list)


Alignment not available.
[Masking step 1 details] [Masking step 2 details] [Filtration details] [Global HMM file]

Phylogeny tree not available.


Alignment and filtration statistics:

Overall family sequences Sequences used for alignment (w/o splice) Sequences kept after filtration [min; median; max] ~average sequence length Alignment length Masked alignment length
176 162 (92%) 123 (70%) [58; 366; 1004] ~319 2065 224