!-) END html_header.tt -->

Family GP000624


Family ID GP000624  add to my list RDF
Family name Lactate/malate dehydrogenase family   suggest a name
Cross-reference(s) PMID:
Identification of phosphoproteins regulated by gibberellin in rice leaf sheath.
16028114 PMID:
Cloning, characterization and prokaryotic expression of cytosolic malate dehydrogenase from Oryza sativa.
15620222 PMID:
Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.
14671022 PMID:
Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.
12766230 PMID:
A novel, non-redox-regulated NAD-dependent malate dehydrogenase from chloroplasts of Arabidopsis thaliana L.
9774405 PMID:
Glyoxysomal malate dehydrogenase and malate synthase from soybean cotyledons (Glycine max L.): enzyme association, antibody production and cDNA cloning.
8547819 PMID:
Structural basis for altered activity of M- and H-isozyme forms of human lactate dehydrogenase.
11276087 PMID:
Refined crystal structure of mitochondrial malate dehydrogenase from porcine heart and the consensus structure for dicarboxylic acid oxidoreductases.
8117664
Family Ontology
Close Hide
molecular_function
L-lactate dehydrogenase activity
GO:0004459 (11%) - L-lactate dehydrogenase activity
malate dehydrogenase activity
GO:0016615 (26%) - malate dehydrogenase activity
malate dehydrogenase (NADP+) activity
GO:0046554 (9%) - malate dehydrogenase (NADP+) activity
Curation status ?
Found in No specificity
Phylogenetic analyzes Did not pass filtration




Clustering level Family ID (number of sequences)
1
Lactate/malate dehydrogenase family (plant-specificity: 9%)
GP000624 (685)
2
Malate Dehydrogenase, NAD-Dependent, Eukaryote/Gamma Proteobacteria Subfamily
GP015749 (345) ,
Malate dehydrogenase, NAD/NADP subfamily
GP016151 (243) ,
L-lactate dehydrogenase subfamily
GP018200 (97)
3 GP040404 (345) , GP041455 (154) , GP042894 (97) ,
(plant-specificity: 9%)
GP044101 (89)
4 GP069857 (345) , GP070832 (154) , GP072397 (95) , GP073628 (89)
Table 1: This table displays which relationship has the selected family with other families in GreenPhyl clustering ?.




Legend:
  • Families (clustering)
    • Sequences are clustered and classified at 4 levels (from less to more stringent).
    • The number between parenthesis indicates the number of sequences in the cluster.
    • Selected family is highlighted like this.
    • Annotated gene families are underlined and gene family name pops up when you move your mouse cursor over.
    • Gene families are coloured in this color when the phylogenetic analyses are available.


Sequence total: 685
Species Count (w/o splice) Count (w/ splice)
7 7
5 5
55 55
16 19
9 9
28 28
10 10
21 21
17 17
25 25
16 16
13 19
10 11
10 10
14 14
14 22
12 16
13 13
12 12
12 12
13 13
11 17
8 8
36 36
16 30
9 9
25 51
11 11
18 18
11 17
41 41
14 14
14 15
14 14
9 12
21 29
9 9


Information to display




(click on chart bars above to get species proteins)


Close InterPro family
IPR Annotation Type % Occurence Specificity
L-lactate/malate dehydrogenase
IPR001557
L-lactate/malate dehydrogenase Family 56 (381) Yes
Malate dehydrogenase, type 1
IPR010097
Malate dehydrogenase, type 1 Family 38 (263) Yes
Malate dehydrogenase, type 2
IPR010945
Malate dehydrogenase, type 2 Family 26 (176) Yes
Malate dehydrogenase, NADP-dependent, plants
IPR011273
Malate dehydrogenase, NADP-dependent, plants Family 9 (60) Yes
Malate dehydrogenase, NAD-dependent, cytosolic
IPR011274
Malate dehydrogenase, NAD-dependent, cytosolic Family 13 (90) Yes
Malate dehydrogenase, type 3
IPR011275
Malate dehydrogenase, type 3 Family 1 (1) Yes
L-lactate dehydrogenase
IPR011304
L-lactate dehydrogenase Family 9 (63) Yes

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
Lactate/malate dehydrogenase, N-terminal
IPR001236
Lactate/malate dehydrogenase, N-terminal Domain 87 (597) No
Malate dehydrogenase, active site
IPR001252
Malate dehydrogenase, active site Active_site 66 (449) No
Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal
IPR015955
Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal Domain 86 (589) No
Lactate/malate dehydrogenase, C-terminal
IPR022383
Lactate/malate dehydrogenase, C-terminal Domain 85 (581) No

Close Domain architecture
Clustering
 



Close Representative InterPro domains - Consensus schema
IPR015955 IPR001557 IPR001252 IPR001236 IPR022383 IPR010097


Build your own display:   ?

Species
Information to display
?


(click on the button above to get your protein list)


Alignment not available.
[Masking step 1 details] [Masking step 2 details] [Filtration details] [Global HMM file]

Phylogeny tree not available.


Alignment and filtration statistics:

Overall family sequences Sequences used for alignment (w/o splice) Sequences kept after filtration [min; median; max] ~average sequence length Alignment length Masked alignment length
685 599 (87%) 494 (72%) [36; 343; 797] ~322 2184 189