Family GP000608


Family ID GP000608  add to my list RDF
Family name Valyl/leucyl/isoleucyl-trna synthetase, class i, anticodon-binding superfamily   suggest a name
Cross-reference(s) PMID:
Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs.
2203971 PMID:
The aminoacyl-tRNA synthetase family: modules at work.
8274143
Family Ontology
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molecular_function
aminoacyl-tRNA editing activity
GO:0002161 (12%) - aminoacyl-tRNA editing activity
isoleucine-tRNA ligase activity
GO:0004822 (6%) - isoleucine-tRNA ligase activity
biological_process
tRNA aminoacylation for protein translation
GO:0006418 (12%) - tRNA aminoacylation for protein translation
isoleucyl-tRNA aminoacylation
GO:0006428 (22%) - isoleucyl-tRNA aminoacylation
valyl-tRNA aminoacylation
GO:0006438 (12%) - valyl-tRNA aminoacylation
Curation status ?
Found in No specificity
Phylogenetic analyzes Did not pass filtration




Clustering level Family ID (number of sequences)
1
Valyl/leucyl/isoleucyl-trna synthetase, class i, anticodon-binding superfamily
GP000608 (509)
2
Valyl-trna synthetase, class ia family
GP016603 (227) , GP016541 (195) ,
(plant-specificity: 11%)
GP019546 (85)
3 GP041214 (227) , GP042316 (105) , GP044434 (90) , GP044433 (85)
4 GP070615 (227) , GP071758 (103) , GP073995 (88) , GP073994 (85)
Table 1: This table displays which relationship has the selected family with other families in GreenPhyl clustering ?.




Legend:
  • Families (clustering)
    • Sequences are clustered and classified at 4 levels (from less to more stringent).
    • The number between parenthesis indicates the number of sequences in the cluster.
    • Selected family is highlighted like this.
    • Annotated gene families are underlined and gene family name pops up when you move your mouse cursor over.
    • Gene families are coloured in this color when the phylogenetic analyses are available.


Sequence total: 509
Species Count (w/o splice) Count (w/ splice)
5 5
7 7
70 70
7 7
8 8
31 31
7 7
10 10
8 8
9 9
10 10
10 13
6 7
8 8
8 8
11 19
8 8
5 5
2 2
8 8
8 8
7 9
7 7
19 19
22 54
7 7
15 28
8 8
10 10
6 10
39 39
14 14
10 10
5 5
7 9
12 15
7 7


Information to display




(click on chart bars above to get species proteins)


Close InterPro family
IPR Annotation Type % Occurence Specificity
Peptidase A8, signal peptidase II
IPR001872
Peptidase A8, signal peptidase II Family 1 (2) Yes
Isoleucine-tRNA ligase
IPR002301
Isoleucine-tRNA ligase Family 22 (111) Yes
Leucine-tRNA ligase, bacterial/mitochondrial
IPR002302
Leucine-tRNA ligase, bacterial/mitochondrial Family 13 (66) Yes
Valine-tRNA ligase
IPR002303
Valine-tRNA ligase Family 26 (132) Yes
Isoleucine-tRNA ligase, type 1
IPR023585
Isoleucine-tRNA ligase, type 1 Family 9 (45) Yes
Isoleucine-tRNA ligase, type 2
IPR023586
Isoleucine-tRNA ligase, type 2 Family 6 (28) Yes

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
Aminoacyl-tRNA synthetase, class I, conserved site
IPR001412
Aminoacyl-tRNA synthetase, class I, conserved site Conserved_site 53 (268) No
Aminoacyl-tRNA synthetase, class Ia
IPR002300
Aminoacyl-tRNA synthetase, class Ia Domain 77 (392) No
Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing domain
IPR009008
Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing domain Domain 64 (325) No
Aminoacyl-tRNA synthetase, class 1a, anticodon-binding
IPR009080
Aminoacyl-tRNA synthetase, class 1a, anticodon-binding Domain 64 (328) No
Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding
IPR013155
Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding Domain 62 (314) No
Rossmann-like alpha/beta/alpha sandwich fold
IPR014729
Rossmann-like alpha/beta/alpha sandwich fold Domain 75 (383) No

Close Domain architecture
Clustering
 



Close Representative InterPro domains - Consensus schema
IPR014729 IPR009080 IPR001412 IPR002300 IPR009008 IPR013155


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Species
Information to display
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Alignment not available.
[Masking step 1 details] [Masking step 2 details] [Filtration details] [Global HMM file]

Phylogeny tree not available.


Alignment and filtration statistics:

Overall family sequences Sequences used for alignment (w/o splice) Sequences kept after filtration [min; median; max] ~average sequence length Alignment length Masked alignment length
509 441 (87%) 267 (52%) [43; 839; 1783] ~691 3834 287