Family GP001019


Family ID GP001019  add to my list RDF
Family name Cystathionine gamma-synthase family   suggest a name
Synonym(s) Cys/met metabolism, pyridoxal phosphate-dependent enzyme
Cross-reference(s) PMID:
The three-dimensional structure of cystathionine beta-lyase from Arabidopsis and its substrate specificity.
11402193
Family Ontology
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molecular_function
cystathionine beta-lyase activity
GO:0004121 (13%) - cystathionine beta-lyase activity
biological_process
'de novo' L-methionine biosynthetic process
GO:0071266 (13%) - 'de novo' L-methionine biosynthetic process
Curation status ?
Found in No specificity
Phylogenetic analyzes Did not pass filtration




Clustering level Family ID (number of sequences)
1
Cystathionine gamma-synthase family (plant-specificity: 9%)
GP001019 (317)
2 GP016432 (237) , GP019117 (80)
3
Cystathionine gamma-synthase subfamily
GP041921 (152) ,
Cystathionine beta-lyase subfamily
GP044978 (85) , GP043951 (80)
4 GP071324 (146) , GP074601 (85) , GP073623 (80) , GP138168 (6)
Table 1: This table displays which relationship has the selected family with other families in GreenPhyl clustering ?.




Legend:
  • Families (clustering)
    • Sequences are clustered and classified at 4 levels (from less to more stringent).
    • The number between parenthesis indicates the number of sequences in the cluster.
    • Selected family is highlighted like this.
    • Annotated gene families are underlined and gene family name pops up when you move your mouse cursor over.
    • Gene families are coloured in this color when the phylogenetic analyses are available.


Sequence total: 317
Species Count (w/o splice) Count (w/ splice)
3 3
3 3
37 37
6 8
5 5
26 26
3 3
7 7
7 7
6 6
4 4
9 11
4 4
4 4
5 5
7 15
4 4
4 4
9 9
7 7
2 2
4 6
3 3
17 17
7 15
4 4
10 17
5 5
8 8
4 6
17 17
7 7
10 11
7 7
4 4
8 11
5 5


Information to display




(click on chart bars above to get species proteins)


Close InterPro family
IPR Annotation Type % Occurence Specificity
Cys/Met metabolism, pyridoxal phosphate-dependent enzyme
IPR000277
Cys/Met metabolism, pyridoxal phosphate-dependent enzyme Family 87 (277) No
Cystathionine beta-lyase, bacterial
IPR006233
Cystathionine beta-lyase, bacterial Family 1 (2) Yes
O-succinylhomoserine sulfhydrylase
IPR006234
O-succinylhomoserine sulfhydrylase Family 1 (1) Yes
O-acetylhomoserine/O-acetylserine sulfhydrylase
IPR006235
O-acetylhomoserine/O-acetylserine sulfhydrylase Family 3 (10) Yes
Cystathionine beta-lyase, eukaryotic
IPR006238
Cystathionine beta-lyase, eukaryotic Family 13 (42) Yes

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
Pyridoxal phosphate-dependent transferase, major region, subdomain 1
IPR015421
Pyridoxal phosphate-dependent transferase, major region, subdomain 1 Domain 81 (257) No
Pyridoxal phosphate-dependent transferase, major region, subdomain 2
IPR015422
Pyridoxal phosphate-dependent transferase, major region, subdomain 2 Domain 76 (241) No
Pyridoxal phosphate-dependent transferase
IPR015424
Pyridoxal phosphate-dependent transferase Domain 87 (276) No

Close Domain architecture
Clustering
 



Close Representative InterPro domains - Consensus schema
IPR015421 IPR015424 IPR015422 IPR000277


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Species
Information to display
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Alignment not available.
[Masking step 1 details] [Masking step 2 details] [Filtration details] [Global HMM file]

Phylogeny tree not available.


Alignment and filtration statistics:

Overall family sequences Sequences used for alignment (w/o splice) Sequences kept after filtration [min; median; max] ~average sequence length Alignment length Masked alignment length
317 282 (89%) 229 (72%) [50; 435; 1170] ~389 2632 264