Family GP000156


Family ID
GP000156  add to my list
Family name
Major Intrinsic family (MIP)   suggest a name
Synonym(s)
Aquaporin
Cross-reference(s)
PMID:
The MIP family of integral membrane channel proteins: sequence comparisons, evolutionary relationships, reconstructed pathway of evolution, and proposed functional differentiation of the two repeated halves of the proteins.
8325040 PMID:
Evolution of the MIP family of integral membrane transport proteins.
2014003 PMID:
From structure to disease: the evolving tale of aquaporin biology.
15340377
Curation status ?
Taxonomic coverage
Gene tree
Family level
1


(click on individual chart bar to display sequence composition below. Several bars can be selected and will remain highlighted)
Sequence total: 1617
Species Sequence Count
15
27
16
26
75
51
46
28
54
37
25
22
27
26
32
71
25
25
24
31
14
25
23
38
68
30
29
31
59
29
29
48
43
54
24
25
29
26
81
33
32
29
22
34
40
39




Close InterPro family
IPR Annotation Type % Occurence Specificity
Major intrinsic protein
IPR000425
Major intrinsic protein Family 97 (1576) No

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
Major intrinsic protein, conserved site
IPR022357
Major intrinsic protein, conserved site Conserved_site 78 (1258) No
Aquaporin-like
IPR023271
Aquaporin-like Homologous_superfamily 98 (1589) No

Close Representative InterPro domains - Consensus schema
IPR000425 IPR023271 IPR022357

Close Domain architecture
Clustering




Note: Alignment too large for online display.
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