Family GP000319


Family ID
GP000319  add to my list
Family name
Putative clathrin assembly protein family   suggest a name
Cross-reference(s)
PMID:
Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains.
12740367 PMID:
Simultaneous binding of PtdIns(4,5)P2 and clathrin by AP180 in the nucleation of clathrin lattices on membranes.
11161218
Curation status ?
Taxonomic coverage
Gene tree
Family level
1


(click on individual chart bar to display sequence composition below. Several bars can be selected and will remain highlighted)
Sequence total: 1163
Species Sequence Count
14
19
13
18
54
39
35
19
20
23
19
14
22
17
28
49
15
16
12
25
9
33
17
43
23
23
25
20
37
23
21
37
21
33
22
28
24
33
58
21
24
21
15
29
23
29




Close InterPro family
IPR Annotation Type % Occurence Specificity
Protein of unknown function DUF872, transmembrane
IPR008590
Protein of unknown function DUF872, transmembrane Family 16 (191) Yes

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
ENTH/VHS
IPR008942
ENTH/VHS Homologous_superfamily 72 (842) No
AP180 N-terminal homology (ANTH) domain
IPR011417
AP180 N-terminal homology (ANTH) domain Domain 74 (863) No
ENTH domain
IPR013809
ENTH domain Domain 70 (814) No
Phosphoinositide-binding clathrin adaptor, domain 2
IPR014712
Phosphoinositide-binding clathrin adaptor, domain 2 Homologous_superfamily 64 (748) No

Close Representative InterPro domains - Consensus schema
IPR013809 IPR008942 IPR011417 IPR014712

Close Domain architecture
Clustering




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