Family GP000446


Family ID
GP000446  add to my list
Family name
2-oxoacid dehydrogenase acyltransferase superfamily   suggest a name
Cross-reference(s)
PMID:
Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.
14671022 PMID:
Lipoic acid-dependent oxidative catabolism of alpha-keto acids in mitochondria provides evidence for branched-chain amino acid catabolism in Arabidopsis.
14764908 PMID:
Cloning and characterization of a dihydrolipoamide acetyltransferase (E2) subunit of the pyruvate dehydrogenase complex from Arabidopsis thaliana.
7890655 PMID:
Refined crystal structure of the catalytic domain of dihydrolipoyl transacetylase (E2p) from Azotobacter vinelandii at 2.6 A resolution.
8487300
Curation status ?
Taxonomic coverage
Gene tree
Family level
1


(click on individual chart bar to display sequence composition below. Several bars can be selected and will remain highlighted)
Sequence total: 523
Species Sequence Count
5
7
7
35
17
18
15
8
7
10
11
6
16
7
15
30
5
6
5
8
6
15
6
6
16
7
9
11
17
8
8
19
9
11
11
12
6
17
26
6
5
6
6
11
10
21




Close InterPro family

No IPR family


Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
Biotin/lipoyl attachment
IPR000089
Biotin/lipoyl attachment Domain 82 (427) No
2-oxoacid dehydrogenase acyltransferase, catalytic domain
IPR001078
2-oxoacid dehydrogenase acyltransferase, catalytic domain Domain 87 (456) No
2-oxo acid dehydrogenase, lipoyl-binding site
IPR003016
2-oxo acid dehydrogenase, lipoyl-binding site Binding_site 77 (405) No
Peripheral subunit-binding domain
IPR004167
Peripheral subunit-binding domain Domain 60 (316) No
Single hybrid motif
IPR011053
Single hybrid motif Homologous_superfamily 82 (431) No
Chloramphenicol acetyltransferase-like domain superfamily
IPR023213
Chloramphenicol acetyltransferase-like domain superfamily Homologous_superfamily 88 (461) No
E3-binding domain superfamily
IPR036625
E3-binding domain superfamily Homologous_superfamily 61 (321) No

Close Representative InterPro domains - Consensus schema
IPR023213 IPR011053 IPR004167 IPR036625 IPR003016 IPR001078 IPR000089

Close Domain architecture
Clustering




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