Family GP001344


Family ID
GP001344  add to my list
Family name
beta-N-acetylhexosaminidase family   suggest a name
Cross-reference(s)
PMID:
Molecular basis of an adult form of Sandhoff disease: substitution of glutamine for arginine at position 505 of the beta-chain of beta-hexosaminidase results in a labile enzyme.
8357844
Curation status ?
Taxonomic coverage
Gene tree
Family level
1


(click on individual chart bar to display sequence composition below. Several bars can be selected and will remain highlighted)
Sequence total: 253
Species Sequence Count
7
3
3
8
4
3
3
5
5
7
3
5
8
5
4
16
6
3
3
4
9
4
3
6
6
6
3
4
3
4
3
6
3
10
9
8
4
6
18
3
2
6
3
5
8
6




Close InterPro family
IPR Annotation Type % Occurence Specificity
Beta-hexosaminidase
IPR025705
Beta-hexosaminidase Family 88 (222) Yes

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
Glycoside hydrolase family 20, catalytic domain
IPR015883
Glycoside hydrolase family 20, catalytic domain Domain 92 (234) No
Glycoside hydrolase superfamily
IPR017853
Glycoside hydrolase superfamily Homologous_superfamily 94 (237) No
Beta-hexosaminidase-like, domain 2
IPR029018
Beta-hexosaminidase-like, domain 2 Homologous_superfamily 81 (204) No
Beta-hexosaminidase, eukaryotic type, N-terminal
IPR029019
Beta-hexosaminidase, eukaryotic type, N-terminal Domain 77 (195) No

Close Representative InterPro domains - Consensus schema
IPR017853 IPR029018 IPR015883 IPR025705 IPR029019

Close Domain architecture
Clustering





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