Family GP002389


Family ID
GP002389  add to my list
Family name
Eukaryotic translation initiation factor 2, alpha subunit family   suggest a name
Cross-reference(s)
PMID:
Yeast translation initiation suppressor sui2 encodes the alpha subunit of eukaryotic initiation factor 2 and shares sequence identity with the human alpha subunit.
2649894 PMID:
The crystal structure of the N-terminal region of the alpha subunit of translation initiation factor 2 (eIF2alpha) from Saccharomyces cerevisiae provides a view of the loop containing serine 51, the target of the eIF2alpha-specific kinases.
14607111 PMID:
The roles of initiation factor 2 and guanosine triphosphate in initiation of protein synthesis.
14532131 PMID:
Universal translation initiation factor IF2/eIF5B.
12762044
Curation status ?
Taxonomic coverage
Magnoliopsida
Gene tree
Family level
1


(click on individual chart bar to display sequence composition below. Several bars can be selected and will remain highlighted)
Sequence total: 117
Species Sequence Count
4
2
1
2
5
8
4
1
4
3
1
1
2
1
5
3
1
1
2
2
2
3
2
1
3
2
2
2
11
2
3
3
3
3
2
2
2
2
4
2
1
1
1
2
2
1




Close InterPro family
IPR Annotation Type % Occurence Specificity
Translation initiation factor 2, alpha subunit
IPR011488 		Translation initiation factor 2, alpha subunit Family 82 (96) Yes

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
S1 domain
IPR003029 		S1 domain Domain 82 (96) No
Nucleic acid-binding, OB-fold
IPR012340 		Nucleic acid-binding, OB-fold Homologous_superfamily 85 (99) No
RNA-binding domain, S1
IPR022967 		RNA-binding domain, S1 Domain 76 (89) No
Translation initiation factor 2, alpha subunit, middle domain superfamily
IPR024054 		Translation initiation factor 2, alpha subunit, middle domain superfamily Homologous_superfamily 78 (91) No

Close Representative InterPro domains - Consensus schema
IPR012340 IPR003029 IPR022967
Translation initiation factor 2, alpha subunit, C-terminal
IPR024055 IPR024054 IPR011488

Close Domain architecture
Clustering





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