Family GP003776


Family ID
GP003776  add to my list
Family name
Autophagy protein 5 family   suggest a name
Synonym(s)
Autophagy-related protein 5
Cross-reference(s)
PMID:
The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation.
11689437 PMID:
A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy.
9852036 PMID:
Apg16p is required for the function of the Apg12p-Apg5p conjugate in the yeast autophagy pathway.
10406794 PMID:
Apg5p functions in the sequestration step in the cytoplasm-to-vacuole targeting and macroautophagy pathways.
10712513
Curation status ?
Taxonomic coverage
Gene tree
Family level
1


(click on individual chart bar to display sequence composition below. Several bars can be selected and will remain highlighted)
Sequence total: 81
Species Sequence Count
1
1
1
3
2
2
2
2
1
3
1
1
4
1
1
7
1
1
4
1
2
2
1
2
3
2
1
2
1
2
1
1
1
1
1
1
3
5
2
1
1
3
1
1




Close InterPro family
IPR Annotation Type % Occurence Specificity
Autophagy-related protein 5
IPR007239
Autophagy-related protein 5 Family 96 (78) Yes

Close Other InterPro signatures

No other significant IPR (i.e. > 25%)


Close Representative InterPro domains - Consensus schema
Autophagy protein Atg5, UblA domain
IPR042527
Autophagy protein Atg5, helix rich domain
IPR042526 IPR007239


Close Domain architecture
Clustering





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