Family GP004158


Family ID
GP004158  add to my list
Family name
Centromere protein Mis12 family   suggest a name
Cross-reference(s)
PMID:
Proper metaphase spindle length is determined by centromere proteins Mis12 and Mis6 required for faithful chromosome segregation.
10398680 PMID:
The mal2p protein is an essential component of the fission yeast centromere.
12242294 PMID:
Human centromere chromatin protein hMis12, essential for equal segregation, is independent of CENP-A loading pathway.
12515822
Curation status ?
Taxonomic coverage
Gene tree
Family level
1


(click on individual chart bar to display sequence composition below. Several bars can be selected and will remain highlighted)
Sequence total: 70
Species Sequence Count
1
1
1
3
2
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1
1
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2
1
1
2
2
1
2
1
2
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1
3
1
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3
2
1
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1
1
1
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2
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1
1
1
4
1
3




Close InterPro family
IPR Annotation Type % Occurence Specificity
Centromere protein Mis12
IPR008685
Centromere protein Mis12 Family 87 (61) Yes

Close Other InterPro signatures

No other significant IPR (i.e. > 25%)


Close Representative InterPro domains - Consensus schema
IPR008685

Close Domain architecture
Clustering





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