Family GP000819


Family ID
GP000819  add to my list
Family name
Potassium channel, two pore-domain family   suggest a name
Cross-reference(s)
PMID:
TASK, a human background K+ channel to sense external pH variations near physiological pH.
9312005 PMID:
TWIK-1, a ubiquitous human weakly inward rectifying K+ channel with a novel structure.
8605869 PMID:
A new family of outwardly rectifying potassium channel proteins with two pore domains in tandem.
7651518
Curation status ?
Taxonomic coverage
Gene tree
Family level
1


(click on individual chart bar to display sequence composition below. Several bars can be selected and will remain highlighted)
Sequence total: 345
Species Sequence Count
4
6
7
4
14
9
9
5
6
19
5
6
10
5
6
18
4
3
3
8
1
9
9
6
13
14
6
4
20
9
6
5
4
9
4
4
5
10
16
6
5
4
6
5
10
4




Close InterPro family
IPR Annotation Type % Occurence Specificity
Two pore domain potassium channel
IPR003280
Two pore domain potassium channel Family 83 (286) No
Two pore domain potassium channel, plant
IPR031144
Two pore domain potassium channel, plant Family 20 (68) Yes

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
EF-hand domain pair
IPR011992
EF-hand domain pair Homologous_superfamily 59 (202) No
Potassium channel domain
IPR013099
Potassium channel domain Domain 97 (333) No
EF-Hand 1, calcium-binding site
IPR018247
EF-Hand 1, calcium-binding site Binding_site 65 (224) No

Close Representative InterPro domains - Consensus schema
IPR011992 IPR018247 IPR013099 IPR003280

Close Domain architecture
Clustering





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