Family GP000127


Family ID
GP000127  add to my list
Family name
O-methyltransferase, eukaryotic comt type family   suggest a name
Synonym(s)
O-methyltransferase family 2
Cross-reference(s)
PMID:
Flavonoid 3'-O-methyltransferase from rice: cDNA cloning, characterization and functional expression.
16412485 PMID:
Characterization of bispecific caffeic acid/5-hydroxyferulic acid O-methyltransferase from aspen.
1368360 PMID:
Crystal structure of aclacinomycin-10-hydroxylase, a S-adenosyl-L-methionine-dependent methyltransferase homolog involved in anthracycline biosynthesis in Streptomyces purpurascens.
14607118 PMID:
Structural basis for the modulation of lignin monomer methylation by caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase.
12084826 PMID:
Structures of two natural product methyltransferases reveal the basis for substrate specificity in plant O-methyltransferases.
11224575
Curation status ?
Taxonomic coverage
Magnoliopsida
Gene tree
Family level
1


(click on individual chart bar to display sequence composition below. Several bars can be selected and will remain highlighted)
Sequence total: 2050
Species Sequence Count
20
17
30
27
70
52
42
53
90
62
25
29
49
102
21
89
55
25
18
17
50
20
21
55
58
42
34
29
67
41
67
35
36
21
40
51
39
23
106
25
41
48
22
98
57
31




Close InterPro family
IPR Annotation Type % Occurence Specificity
O-methyltransferase COMT-type
IPR016461 		O-methyltransferase COMT-type Family 93 (1904) No

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
O-methyltransferase domain
IPR001077 		O-methyltransferase domain Domain 90 (1839) No
Plant methyltransferase dimerisation
IPR012967 		Plant methyltransferase dimerisation Domain 73 (1491) No
S-adenosyl-L-methionine-dependent methyltransferase
IPR029063 		S-adenosyl-L-methionine-dependent methyltransferase Homologous_superfamily 90 (1846) No
Winged helix-like DNA-binding domain superfamily
IPR036388 		Winged helix-like DNA-binding domain superfamily Homologous_superfamily 80 (1630) No
Winged helix DNA-binding domain superfamily
IPR036390 		Winged helix DNA-binding domain superfamily Homologous_superfamily 77 (1588) No

Close Representative InterPro domains - Consensus schema
IPR029063 IPR036390 IPR036388 IPR012967 IPR001077 IPR016461

Close Domain architecture
Clustering




Note: Alignment too large for online display.
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