Family GP001798


Family ID
GP001798  add to my list
Family name
Phosphopantothenoylcysteine decarboxylase family   suggest a name
Synonym(s)
Phosphopantothenoylcysteine decarboxylase/phosphopantothenate - cysteine ligase
Cross-reference(s)
PMID:
Arabidopsis thaliana AtHAL3: a flavoprotein related to salt and osmotic tolerance and plant growth.
10652125 PMID:
Arabidopsis thaliana flavoprotein AtHAL3a catalyzes the decarboxylation of 4'-Phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis.
11279129 PMID:
Molecular characterization of the Arabidopsis thaliana flavoprotein AtHAL3a reveals the general reaction mechanism of 4'-phosphopantothenoylcysteine decarboxylases.
11923307 PMID:
Crystal structure of the plant PPC decarboxylase AtHAL3a complexed with an ene-thiol reaction intermediate.
12614618
Curation status ?
Taxonomic coverage
Magnoliopsida
Gene tree
Family level
1


(click on individual chart bar to display sequence composition below. Several bars can be selected and will remain highlighted)
Sequence total: 142
Species Sequence Count
4
2
2
3
6
5
2
3
1
3
2
1
3
1
4
12
2
2
2
2
1
10
1
8
2
1
1
1
3
3
5
4
1
1
2
1
3
4
8
2
1
8
1
3
2
3




Close InterPro family
IPR Annotation Type % Occurence Specificity
Coenzyme A biosynthesis bifunctional protein CoaBC
IPR005252 		Coenzyme A biosynthesis bifunctional protein CoaBC Family 2 (3) Yes

Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
Flavoprotein
IPR003382 		Flavoprotein Domain 97 (138) No
Flavin prenyltransferase-like
IPR036551 		Flavin prenyltransferase-like Homologous_superfamily 99 (140) No

Close Representative InterPro domains - Consensus schema
IPR036551 IPR003382

Close Domain architecture
Clustering





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