Family GP000067


Family ID
GP000067  add to my list
Family name
Papain superfamily   suggest a name
Cross-reference(s)
PMID:
A peptide derived from the C-terminal part of a plant cysteine protease folds into a stack of two beta-hairpins, a scaffold present in the emerging family of granulin-like growth factors.
11298924 PMID:
Structure of papain.
5681232 PMID:
Molecular cloning of a protein associated with soybean seed oil bodies that is similar to thiol proteases of the papain family.
2380191
Curation status ?
Taxonomic coverage
Gene tree
Family level
1


(click on individual chart bar to display sequence composition below. Several bars can be selected and will remain highlighted)
Sequence total: 2685
Species Sequence Count
40
38
20
65
135
87
80
55
65
48
36
17
54
42
34
91
31
24
29
25
62
43
50
84
116
69
66
67
111
45
64
46
38
54
53
70
41
49
136
39
35
42
28
156
42
63




Close InterPro family

No IPR family


Close Other InterPro signatures
IPR Annotation Type % Occurence Specificity
Cysteine peptidase, cysteine active site
IPR000169
Cysteine peptidase, cysteine active site Active_site 57 (1532) No
Peptidase C1A, papain C-terminal
IPR000668
Peptidase C1A, papain C-terminal Domain 86 (2300) No
Cathepsin propeptide inhibitor domain (I29)
IPR013201
Cathepsin propeptide inhibitor domain (I29) Domain 71 (1915) No
Cysteine peptidase, histidine active site
IPR025660
Cysteine peptidase, histidine active site Active_site 63 (1688) No
Cysteine peptidase, asparagine active site
IPR025661
Cysteine peptidase, asparagine active site Active_site 63 (1681) No
Papain-like cysteine peptidase superfamily
IPR038765
Papain-like cysteine peptidase superfamily Homologous_superfamily 92 (2475) No
Papain-like cysteine endopeptidase
IPR039417
Papain-like cysteine endopeptidase Domain 71 (1893) No

Close Representative InterPro domains - Consensus schema
IPR038765 IPR000169 IPR000668 IPR025660 IPR013201 IPR025661 IPR039417

Close Domain architecture
Clustering




Note: Alignment too large for online display.
Download alignment file: 






You can filter species displayed in the phylogenomic tree by checking the species you want:
Species

Download tree file: 





for (default: all):
Species


(click on the button above to get your homolog prediction list)